{"id":6288,"date":"2026-10-19T09:48:43","date_gmt":"2026-10-19T09:48:43","guid":{"rendered":"https:\/\/phd.hi.is\/doktorsvorn\/doktorsvorn-i-efnafraedi-maicol-cipriani\/"},"modified":"2026-10-19T09:48:43","modified_gmt":"2026-10-19T09:48:43","slug":"doktorsvorn-i-efnafraedi-maicol-cipriani","status":"publish","type":"phd_defence","link":"https:\/\/phd.hi.is\/en\/doktorsvorn\/doktorsvorn-i-efnafraedi-maicol-cipriani\/","title":{"rendered":"Doktorsv\u00f6rn \u00ed efnafr\u00e6\u00f0i &#8211; Maicol Cipriani"},"content":{"rendered":"<div class=\"field-items\">\n<div class=\"field-item even\" property=\"content:encoded\">\n<p><strong>Doktorsefni:<\/strong>\u00a0Maicol Cipriani<\/p>\n<p><strong>Heiti ritger\u00f0ar:<\/strong> Rafeindadrifin efnahv\u00f6rf vi\u00f0 \u00f6rt\u00e6kniprentun yfirbor\u00f0a og \u00ed geislalyfjame\u00f0fer\u00f0 krabbameins (Low energy electron-induced reactions of model compounds for nano-scale fabrication and for application in chemoradiotherapy)<\/p>\n<p><strong>Andm\u00e6lendur:\u00a0 <\/strong>Dr. Janina Kopyra, d\u00f3sent vi\u00f0 Siedlce University, P\u00f3llandi<br \/> Dr. M\u00e1rcio Teixeira do Nascimento Varella, d\u00f3sent vi\u00f0 University of S\u00e3o Paolo, Brasil\u00edu<\/p>\n<p><strong>Lei\u00f0beinandi:<\/strong>\u00a0Dr. Oddur Ing\u00f3lfsson, pr\u00f3fessor vi\u00f0 Raunv\u00edsindadeild H\u00cd<\/p>\n<p><strong>Einnig \u00ed doktorsnefnd:<\/strong> Dr. Armin G\u00f6lzh\u00e4user, pr\u00f3fessor vi\u00f0 Bielefeld University, \u00de\u00fdskalandi<br \/> Dr. Ragnar Bj\u00f6rnsson, v\u00edsindama\u00f0ur vi\u00f0 Laboratoire de chimie et biologie des m\u00e9taux, CEA, Grenoble, Frakklandi<\/p>\n<p><strong>Doktorsv\u00f6rn st\u00fdrir:<\/strong>\u00a0Dr. Einar \u00d6rn Sveinbj\u00f6rnsson, pr\u00f3fessor og deildarforseti Raunv\u00edsindadeildar H\u00cd<\/p>\n<p><strong>\u00c1grip<\/strong><\/p>\n<p>Vixverkun lagorkurafeinda (LEEs) vi\u00f0 \u00f3hla\u00f0nar sameindir er mikilv\u00e6g fyrir margv\u00edslegar a\u00f0fer\u00f0ir. \u00d6rprentun me\u00f0 sk\u00f6rpum rafeindageisla (en: focused electron beam induced deposition (FEBID)) er ein svolei\u00f0is a\u00f0fer\u00f0 en h\u00fan er notu\u00f0 til a\u00f0 \u00fatb\u00faa str\u00fakt\u00fara \u00e1 nan\u00f3metraskala \u00fat fr\u00e1 undanfarasameindum, sem eru yfirleitt \u00e1 formi l\u00edfr\u00e6nna m\u00e1lmkomplexa, sem eru a\u00f0soga\u00f0ir \u00e1 yfirbor\u00f0. A n\u00faverandi stigi stendur \u00feessi t\u00e6kni frammi fyrir \u00e1skorunum um hva\u00f0 var\u00f0ar hreinleika og \u00e1fallsefnis. \u00deessar \u00e1skoranir eru a\u00f0allega raktar til \u00f3\u00e6skilegra lagorku rafeinda sem myndast \u00feegar rafeindageisli fellur \u00e1 yfirbor\u00f0. \u00d3\u00e6skilegu rafeindirnar dreifast v\u00edtt og breytt og geta framkalla\u00f0 \u00f3\u00e6skileg hli\u00f0arhvorf og ni\u00f0urbrots undanfarasameindanna.<\/p>\n<p>V\u00edxlverkun l\u00e1gorkurafeinda getur einnig gegnt mikilv\u00e6gu hlutverki \u00ed krabbameinslyfjame\u00f0fer\u00f0 en \u00fe\u00e1 eru geislan\u00e6misefni notu\u00f0 til \u00feess a\u00f0 gera krabbameinsfrumur n\u00e6mari fyrir geislun. Synt hefur veri\u00f0 fram a a\u00f0 v\u00edxlverkun l\u00e1gorkurafeinda, sem myndast vi\u00f0 samspil jonandi geislunar vi\u00f0 l\u00edkamsvefi, getur v\u00edxlast vi\u00f0 geislan\u00e6misefni og framleitt sindurefni sem geta valdi\u00f0 DNA skemmdum.<\/p>\n<p>Til \u00feess a\u00f0 b\u00e6ta afk\u00f6st FEBID undanfarasameinda og geislan\u00e6misefna er mikilv\u00e6gt a\u00f0 rannsaka orkunotkun rafeindaframk\u00f6llunar ferla. Lagorkurafeindir geta framkalla\u00f0 sundrun me\u00f0 fjorum mismunandi ferlum: Rjufandi rafeindaralagningu (en: dissociative electronc attachment (DEA)), rjufandi jonun (en: dissociative ionization (DI)), tviskautsrof (en: dipolar dissociation (DD)) e\u00f0a hlutlausurofi (en: neutral dissocation (ND)). Lagorkurafeinda vixlverkanir hafa oft veri\u00f0 rannsaka\u00f0ar i gasfasatilraunum vi\u00f0 arekstra stakra rafeinda og sameinda, me\u00f0 t\u00e6kjum sem hafa kross sameinda\/rafeindageisla.<\/p>\n<p>\u00cd \u00feessu doktorsverkefni er l\u00e1gorkurafeinda framkalla\u00f0 ni\u00f0urbrot FEBID undanfarasameind og nokkra lifefnasambanda til notkunar i geislalyfjame\u00f0fer\u00f0 sko\u00f0u\u00f0 \u00e1 gasformi, me\u00f0 s\u00e9rstaka \u00e1herslu a sundrandi rafeindatengingu (DEA) og sundrunarjonunarferli (DI).<\/p>\n<p>FEBID forverarasameindir sem hafa veri\u00f0 valdir fyrir \u00feetta verkefni eru (\u03b73-C3H5)Ru(CO)3Br og cis-Pt(CO)2Br2. Fyrir (\u03b73-C3H5)Ru(CO)3Br var ger\u00f0 umfangsmikil k\u00f6nnun a sundrandi jonun i framhaldi af fyrri rannsoknum a \u00feessu efnasambandi. Fyrir cis-Pt(CO)2Br2 voru b\u00e6\u00f0i sundru\u00f0 rafeindatenging og sundru\u00f0 jonun sko\u00f0u\u00f0, me\u00f0 meiri \u00e1herslu a sundrandi rafeindatengingu, og ni\u00f0urst\u00f6\u00f0urnar bornar saman vi\u00f0 fyrri gasfasa sundrunarrafeindatengingu ranns\u00f3knir \u00e1 cis-Pt(CO)2Cl2 og cis-Pt(NH3)2Cl2, me\u00f0 yfirbor\u00f0sranns\u00f3knum \u00e1 cis-Pt(CO)2Cl2 og me\u00f0 FEBID tilraunum \u00e1 cis-Pt(CO)2Br2 og cis-Pt(CO)2Cl2.<\/p>\n<p>Me\u00f0 \u00fea\u00f0 a\u00f0 markmi\u00f0i a\u00f0 auka n\u00e6mni geislan\u00e6misefna gagnvart l\u00e1gorku rafeindum voru ger\u00f0ar umfangsmiklar rafeindatengingarranns\u00f3knir \u00e1 l\u00edkanefnasamb\u00f6ndunum pentafluorothiophenol, 2-fluorothiophenol og pentafluorobenzoic acid, \u00fear sem vi\u00f0 k\u00f6nnu\u00f0um perfl\u00faorun og hlutlausa HF myndun sem hugsanlega lei\u00f0 til a\u00f0 stu\u00f0la a\u00f0 sundrandi rafeind tengingarvi\u00f0br\u00f6g\u00f0. Ni\u00f0urst\u00f6\u00f0urnar voru bornar saman vi\u00f0 fyrri vinnu um rafeindatengingu vi\u00f0 pentafl\u00faorfen\u00f3l og bens\u00f3s\u00fdru.<\/p>\n<p><strong>Um doktorsefni\u00f0<\/strong><\/p>\n<p>Maicol Cipriani f\u00e6ddist \u00e1 \u00cdtal\u00edu \u00e1ri\u00f0 1991. Hann h\u00f3f doktorsn\u00e1m vi\u00f0 H\u00e1sk\u00f3la \u00cdslands \u00ed \u00e1g\u00fast 2017.<\/p>\n<\/div><\/div>","protected":false},"featured_media":5148,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_phd_date_start":"2022-06-16T13:00:00+00:00","_phd_date_end":"2022-06-16T16:00:00+00:00","_phd_location":"A\u00f0albygging H\u00e1t\u00ed\u00f0arsalur","_phd_admission":"A\u00f0gangur \u00f3keypis","_phd_thesis_title":"Rafeindadrifin efnahv\u00f6rf vi\u00f0 \u00f6rt\u00e6kniprentun yfirbor\u00f0a og \u00ed geislalyfjame\u00f0fer\u00f0 krabbameins (Low energy electron-induced reactions of model compounds for nano-scale fabrication and for application in chemoradiotherapy)","_phd_source_url":"https:\/\/gamli.hi.is\/vidburdir\/doktorsvorn_i_efnafraedi_maicol_cipriani","_phd_source_node_id":"384613","_phd_source_type":"vidburdir","_phd_member_id":817,"footnotes":""},"phd_school":[101,93],"phd_discipline":[102],"class_list":["post-6288","phd_defence","type-phd_defence","status-publish","has-post-thumbnail","hentry","phd_school-raunvisindadeild","phd_school-verkfraedi-og-natturuvisindasvid","phd_discipline-phd-i-efnafraedi"],"_links":{"self":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_defence\/6288","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_defence"}],"about":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/types\/phd_defence"}],"version-history":[{"count":0,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_defence\/6288\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/media\/5148"}],"wp:attachment":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/media?parent=6288"}],"wp:term":[{"taxonomy":"phd_school","embeddable":true,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_school?post=6288"},{"taxonomy":"phd_discipline","embeddable":true,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_discipline?post=6288"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}