{"id":6197,"date":"2026-10-19T09:48:37","date_gmt":"2026-10-19T09:48:37","guid":{"rendered":"https:\/\/phd.hi.is\/doktorsvorn\/doktorsvorn-i-lifverkfraedi-adrianna-milewska\/"},"modified":"2026-10-19T09:48:37","modified_gmt":"2026-10-19T09:48:37","slug":"doktorsvorn-i-lifverkfraedi-adrianna-milewska","status":"publish","type":"phd_defence","link":"https:\/\/phd.hi.is\/en\/doktorsvorn\/doktorsvorn-i-lifverkfraedi-adrianna-milewska\/","title":{"rendered":"Doktorsv\u00f6rn \u00ed l\u00edfverkfr\u00e6\u00f0i -Adrianna Milewska"},"content":{"rendered":"<div class=\"field-items\">\n<div class=\"field-item even\" property=\"content:encoded\">\n<p>Streymi:\u00a0 <a href=\"https:\/\/livestream.com\/hi\/doktorsvornadriannamilewska\">https:\/\/livestream.com\/hi\/doktorsvornadriannamilewska<\/a><\/p>\n<p><strong>Doktorsefni:<\/strong>\u00a0Adrianna Milewska<\/p>\n<p><strong>Heiti ritger\u00f0ar:<\/strong>\u00a0\u00der\u00f3un SERS yfirbor\u00f0a til greiningar \u00e1 s\u00e9rh\u00e6fingu mesenk\u00edmal stofnfruma (Development of SERS substrates for detecting differentiation in mesenchymal stromal cells)<\/p>\n<p><strong>Andm\u00e6lendur:<\/strong> Dr. Laura Fabris, d\u00f3sent vi\u00f0 Rutgers University \u00ed New Jersey, Bandar\u00edkjunum<br \/>  Dr. Mads Bergholt, lektor vi\u00f0 King&#8217;s College, London<\/p>\n<p><strong>Lei\u00f0beinendur:<\/strong>\u00a0Dr. Kristj\u00e1n Le\u00f3sson, \u00fer\u00f3unarstj\u00f3ri DTE ehf.<br \/>  Dr. \u00d3lafur E. Sigurj\u00f3nsson, pr\u00f3fessor vi\u00f0 H\u00e1sk\u00f3lann \u00ed Reykjav\u00edk og forst\u00f6\u00f0uma\u00f0ur ranns\u00f3kna og n\u00fdsk\u00f6punar og stofnfrumuvinnslu Bl\u00f3\u00f0bankans<br \/>  Dr. Unnar B. Arnalds, pr\u00f3fessor vi\u00f0 Raunv\u00edsindadeild H\u00e1sk\u00f3la \u00cdslands<\/p>\n<p><strong>Umsj\u00f3narkennari:<\/strong> Dr. Sigur\u00f0ur Brynj\u00f3lfsson, pr\u00f3fessor vi\u00f0 I\u00f0na\u00f0arverkfr\u00e6\u00f0i-, v\u00e9laverkfr\u00e6\u00f0i- og t\u00f6lvunarfr\u00e6\u00f0ideild H\u00e1sk\u00f3la \u00cdslands<\/p>\n<p><strong>\u00a0<\/strong><strong>Doktorsv\u00f6rn st\u00fdrir:<\/strong>\u00a0Dr. R\u00fanar Unn\u00fe\u00f3rsson, pr\u00f3fessor og deildarforseti I\u00f0na\u00f0arverkfr\u00e6\u00f0i-, v\u00e9laverkfr\u00e6\u00f0i- og t\u00f6lvunarfr\u00e6\u00f0ideildar H\u00e1sk\u00f3la \u00cdslands<\/p>\n<p><strong>\u00c1grip<\/strong><\/p>\n<p>Til a\u00f0 skilja betur \u00fe\u00e1 sameindafr\u00e6\u00f0ilegu ferla sem st\u00fdra s\u00e9rh\u00e6fingu mannafruma, eins og t.d. mesenk\u00edmal bandvefsfruma, er mikilv\u00e6gt a\u00f0 b\u00faa yfir vi\u00f0eigandi greiningart\u00e6kni. Me\u00f0al m\u00f6gulegra lei\u00f0a til a\u00f0 rannsaka sl\u00edkar frumur \u00e1n inngrips er yfirbor\u00f0sm\u00f6gnu\u00f0 Raman lj\u00f3sdreifing (SERS) en me\u00f0 henni m\u00e1 greina l\u00edfr\u00e6nar sameindir, sta\u00f0setningu \u00feeirra, uppbyggingu og v\u00edxlverkun \u00feeirra \u00e1 milli. \u00deessi a\u00f0fer\u00f0 hefur \u00fe\u00f3 n\u00e1\u00f0 takmarka\u00f0ri \u00fatbrei\u00f0slu \u00fear sem skortur er \u00e1 vi\u00f0eigandi yfirbor\u00f0um og samh\u00e6f\u00f0um m\u00e6lia\u00f0fer\u00f0um, auk \u00feess hve erfitt er a\u00f0 \u00fe\u00fd\u00f0a litr\u00f3fsuppl\u00fdsingarnar yfir \u00ed n\u00fdtanleg g\u00f6gn. \u00deessi ritger\u00f0 fjallar um \u00fer\u00f3un yfirbor\u00f0a sem gefa m\u00f6guleika \u00e1 a\u00f0 framkv\u00e6ma samfelldar m\u00e6lingar \u00e1 frumum og \u00feeim sameindal\u00edfr\u00e6\u00f0ilegu ferlum sem eiga s\u00e9r sta\u00f0 innan \u00feeirra. A\u00f0fer\u00f0afr\u00e6\u00f0in var n\u00fdtt s\u00e9rstaklega til a\u00f0 rannsaka beins\u00e9rh\u00e6fingu mesenk\u00edmal bandvefsfruma, me\u00f0 \u00fev\u00ed a\u00f0 fylgjast me\u00f0 breytingum sem \u00e1ttu s\u00e9r sta\u00f0 \u00ed frumuhimnu vi\u00f0 s\u00e9rh\u00e6finguna. SERS-virk yfirbor\u00f0 voru \u00fatb\u00fain \u00e1 gler\u00feynnum me\u00f0 endurtekinni h\u00fa\u00f0un og hitame\u00f0h\u00f6ndlun \u00f6r\u00feunnra laga af gulli. S\u00fdnt var fram \u00e1 framlei\u00f0slua\u00f0fer\u00f0in skila\u00f0i yfirbor\u00f0um me\u00f0 brei\u00f0a st\u00e6r\u00f0ardreifingu gullagna \u00ed nan\u00f3st\u00e6r\u00f0 og jafna dreifingu sterkrar yfirbor\u00f0sm\u00f6gnunar innfallandi rafsegulgeislunar. T\u00f6lulegir \u00fatreikningar \u00e1 m\u00f6gnunarstu\u00f0lum voru framkv\u00e6mdir til a\u00f0 tryggja h\u00e1a og jafndreif\u00f0a m\u00f6gnun litr\u00f3fsmerkis yfir st\u00e6rri sv\u00e6\u00f0i. Ni\u00f0urst\u00f6\u00f0ur \u00fatreikninga voru sta\u00f0festar me\u00f0 tilraunum sem s\u00fdndu fram \u00e1 allt a\u00f0 millj\u00f3nfalda m\u00f6gnun Raman lj\u00f3sdreifingar vi\u00f0 yfirbor\u00f0in. L\u00edfsamh\u00e6fni yfirbor\u00f0anna var sannreynd me\u00f0 l\u00edfvirknipr\u00f3fum og fl\u00farlj\u00f3munarlitun sem sta\u00f0festu a\u00f0 yfirbor\u00f0in s\u00fdndu e\u00f0lilegan frumuv\u00f6xt og fj\u00f6lgun. Gagnsemi yfirbor\u00f0anna vi\u00f0 ranns\u00f3knir \u00e1 frumum yfir lengra t\u00edmabil var sta\u00f0fest me\u00f0 \u00fev\u00ed a\u00f0 fylgja eftir breytingum \u00ed Raman-r\u00f3fum fr\u00e1 frumuhimnum mesenk\u00edmal bandvefsfruma vi\u00f0 beins\u00e9rh\u00e6fingu. Svipger\u00f0 frumanna var sta\u00f0fest samhli\u00f0a me\u00f0 st\u00f6\u00f0lu\u00f0um a\u00f0fer\u00f0um. Ni\u00f0urst\u00f6\u00f0ur ranns\u00f3knana sta\u00f0festu a\u00f0 yfirbor\u00f0in sem \u00fer\u00f3u\u00f0 voru n\u00fdtast vel til a\u00f0 fylgja eftir breytingum \u00ed samsetningu frumuhimna vi\u00f0 beins\u00e9rh\u00e6fingu \u00fear sem \u00feau sameina sm\u00e1sj\u00e1rmyndat\u00f6ku og litr\u00f3fsgreiningu sem birtir efnasamsetningu og efnabreytingar vi\u00f0 frumuhimnu, \u00e1n inngrips. Yfirbor\u00f0in voru einnig n\u00fdtt til ranns\u00f3kna \u00e1 lifandi trefjak\u00edmfrumum sem g\u00e1fu frekari sta\u00f0festingu \u00e1 \u00fev\u00ed a\u00f0 hvorki yfirbor\u00f0in sj\u00e1lf n\u00e9 lj\u00f3s\u00f6rvunin hef\u00f0u neikv\u00e6\u00f0 \u00e1hrif \u00e1 frumurnar. A\u00f0fer\u00f0ir \u00fe\u00e6r sem kynntar eru h\u00e9r gefa \u00fev\u00ed fyrirheit um a\u00f0 \u00fe\u00e6r megi n\u00fdta til a\u00f0 fylgjast me\u00f0 \u00fdmsum frumubreytingum, svo sem beins\u00e9rh\u00e6fingu l\u00edfandi mesenk\u00edmal bandvefsfruma, \u00ed raunt\u00edma og \u00e1n inngrips.<\/p>\n<p><strong>Um doktorsefni\u00f0<\/strong><\/p>\n<p>Adrianna Milewska er f\u00e6dd \u00ed Gda\u0144sk \u00ed P\u00f3llandi \u00e1ri\u00f0 1992. H\u00fan lauk grunnn\u00e1mi \u00ed verkfr\u00e6\u00f0i (Biomedical Engineering) fr\u00e1 T\u00e6knih\u00e1sk\u00f3lanum \u00ed Gda\u0144sk \u00e1ri\u00f0 2015 og meistaragr\u00e1\u00f0u \u00ed sama fagi \u00e1ri\u00f0 2016, en \u00fea\u00f0 var unni\u00f0 \u00ed samstarfi T\u00e6knih\u00e1sk\u00f3lans \u00ed Gda\u0144sk, H\u00e1sk\u00f3lans \u00ed Reykjav\u00edk og Bl\u00f3\u00f0bankans. Adrianna starfa\u00f0i sem verkefnisstj\u00f3ri hj\u00e1 N\u00fdsk\u00f6punarmi\u00f0st\u00f6\u00f0 \u00cdslands 2017-2018, \u00fear til h\u00fan h\u00f3f doktorsn\u00e1m \u00ed l\u00edfverkfr\u00e6\u00f0i vi\u00f0 H\u00e1sk\u00f3la \u00cdslands hausti\u00f0 2018. H\u00fan starfar n\u00fa sem v\u00edsindama\u00f0ur hj\u00e1 lyfjafyrirt\u00e6kinu Alvotech \u00ed Reykjav\u00edk.<\/p>\n<\/div><\/div>","protected":false},"featured_media":5253,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_phd_date_start":"2021-08-20T14:00:00+00:00","_phd_date_end":"2021-08-20T16:00:00+00:00","_phd_location":"A\u00f0albygging H\u00e1t\u00ed\u00f0arsalur","_phd_admission":"A\u00f0gangur \u00f3keypis","_phd_thesis_title":"\u00der\u00f3un SERS yfirbor\u00f0a til greiningar \u00e1 s\u00e9rh\u00e6fingu mesenk\u00edmal stofnfruma (Development of SERS substrates for detecting differentiation in mesenchymal stromal cells)","_phd_source_url":"https:\/\/gamli.hi.is\/vidburdir\/doktorsvorn_i_lifverkfraedi_adrianna_milewska","_phd_source_node_id":"378393","_phd_source_type":"vidburdir","_phd_member_id":720,"footnotes":""},"phd_school":[108,93],"phd_discipline":[129],"class_list":["post-6197","phd_defence","type-phd_defence","status-publish","has-post-thumbnail","hentry","phd_school-idnadarverkfraedi-velaverkfraedi-og-tolvunarfraedideild","phd_school-verkfraedi-og-natturuvisindasvid","phd_discipline-phd-i-lifverkfraedi"],"_links":{"self":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_defence\/6197","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_defence"}],"about":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/types\/phd_defence"}],"version-history":[{"count":0,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_defence\/6197\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/media\/5253"}],"wp:attachment":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/media?parent=6197"}],"wp:term":[{"taxonomy":"phd_school","embeddable":true,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_school?post=6197"},{"taxonomy":"phd_discipline","embeddable":true,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_discipline?post=6197"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}