{"id":6143,"date":"2026-10-19T09:48:33","date_gmt":"2026-10-19T09:48:33","guid":{"rendered":"https:\/\/phd.hi.is\/doktorsvorn\/doktorsvorn-i-liffraedi-sheeba-santhini-basil\/"},"modified":"2026-10-19T09:48:33","modified_gmt":"2026-10-19T09:48:33","slug":"doktorsvorn-i-liffraedi-sheeba-santhini-basil","status":"publish","type":"phd_defence","link":"https:\/\/phd.hi.is\/en\/doktorsvorn\/doktorsvorn-i-liffraedi-sheeba-santhini-basil\/","title":{"rendered":"Doktorsv\u00f6rn \u00ed l\u00edffr\u00e6\u00f0i – Sheeba Santhini Basil"},"content":{"rendered":"
\n
\n

Doktorsefni:<\/strong>\u00a0Sheeba Santhini Basil<\/p>\n

Heiti ritger\u00f0ar:<\/strong>\u00a0Sameindagreining \u00e1 himnusk\u00f3f (Peltigera membranacea) me\u00f0 kjarns\u00fdrura\u00f0greiningu og l\u00fdsing \u00e1 n\u00fdrri fl\u00e9ttutegund, foldarsk\u00f3f (Peltigera islandica)<\/p>\n

Andm\u00e6lendur:<\/strong>
Dr. Imke Scmitt, pr\u00f3fessor vi\u00f0 deild um vistfr\u00e6\u00f0i, \u00fer\u00f3unarfr\u00e6\u00f0i og fj\u00f6lbreytileika, Goethe h\u00e1sk\u00f3lanum \u00ed Frankfurt, \u00de\u00fdskalandi.<\/p>\n

Dr. Kristinn P. Magn\u00fasson, pr\u00f3fessor vi\u00f0 au\u00f0lindadeild H\u00e1sk\u00f3lans \u00e1 Akureyri.<\/p>\n

Lei\u00f0beinandi:<\/strong>\u00a0Dr. \u00d3lafur S. Andr\u00e9sson, pr\u00f3fessor vi\u00f0 L\u00edf- og umhverfisv\u00edsindadeild H\u00e1sk\u00f3la \u00cdslands.<\/p>\n

Einnig \u00ed doktorsnefnd: <\/strong><\/p>\n

Dr. Vivian P. W. Miao, s\u00e9rfr\u00e6\u00f0ingur vi\u00f0 \u00f6rveru- og \u00f3n\u00e6misfr\u00e6\u00f0ideild H\u00e1sk\u00f3lans \u00ed Bresku K\u00f3lumb\u00edu, Kanada.
Dr. Zophon\u00edas Oddur J\u00f3nsson, pr\u00f3fessor vi\u00f0 L\u00edf- og umhverfisv\u00edsindadeild H\u00e1sk\u00f3la \u00cdslands.
Dr. \u00d3lafur H\u00e9\u00f0inn Fri\u00f0j\u00f3nsson, faglegur lei\u00f0togi k\u00f6nnunar og hagn\u00fdtingar erf\u00f0aau\u00f0linda hj\u00e1 Mat\u00eds<\/p>\n

Doktorsv\u00f6rn st\u00fdrir:<\/strong>\u00a0Dr. Anna D\u00f3ra S\u00e6\u00fe\u00f3rsd\u00f3ttir, pr\u00f3fessor og deildarforseti L\u00edf- og umhverfisv\u00edsindadeildar H\u00e1sk\u00f3la \u00cdslands.<\/p>\n

\u00c1grip<\/strong><\/p>\n

Fl\u00e9ttur eru vel \u00feekkt d\u00e6mi um saml\u00edfi sem b\u00e1\u00f0ir a\u00f0ilar hafa gagn af. Bl\u00e1bakter\u00edur e\u00f0a gr\u00e6n\u00fe\u00f6rungar sj\u00e1 um lj\u00f3still\u00edfun en sveppurinn er af oftast af fylkingu asksveppa. Sveppirnir veita bl\u00e1bakter\u00edunum skj\u00f3l, n\u00e6ringu og raka, en f\u00e1 \u00e1 m\u00f3ti n\u00fdtanlegt kolvetni og nitur. Sameindagreining getur veitt inns\u00fdn \u00ed e\u00f0li saml\u00edfis hj\u00e1 fl\u00e9ttum svo sem himnusk\u00f3f (Peltigera membranacea), en \u00fear sem ekki er gerlegt a\u00f0 r\u00e6kta fl\u00e9ttuna \u00fearf a\u00f0 einangra st\u00f3rsameindir svo sem kjarns\u00fdrur og pr\u00f3tein \u00far s\u00fdnum fengnum beint \u00far n\u00e1tt\u00farunni. H\u00e9r er ger\u00f0 grein fyrir erf\u00f0amengi svepphluta himnusk\u00f3far, \u00e1samt greiningu \u00e1 umritamengjum og DNA met\u00fdleringu. Erf\u00f0amengjab\u00fatarnir 3.033 eru samtals um 43 milj\u00f3nir basapara me\u00f0 44,4% G+C hlutfall. Sett voru saman umritas\u00f6fn \u00far alls 43 milj\u00f3num ra\u00f0a \u00far Illumina ra\u00f0greiningum. S\u00f6fnin voru fengin ur \u00ferenns konar vefjum; \u00feali, r\u00e6tlingum og askhirslum, og fr\u00e1 \u00feremur t\u00edmaskei\u00f0um. Trinity samr\u00f6\u00f0unarforriti\u00f0 gaf samtals 110.092 umrit me\u00f0 lengdir fr\u00e1 200 til 18.258 basa. Uppl\u00fdsingar um umrit voru s\u00ed\u00f0an n\u00fdtt \u00ed forritinu AUGUSTUS til a\u00f0 \u00fatb\u00faa gl\u00f3sa\u00f0 erf\u00f0amengi (Pmem v1.1) me\u00f0 16.400 pr\u00f3teint\u00e1knandi genum \u00e1samt uppl\u00fdsingum um var\u00f0veitt am\u00edn\u00f3s\u00fdrustef og l\u00edklega ens\u00edmvirkni (EC n\u00famer). Alls 2.505 afleidd pr\u00f3tein voru flokku\u00f0 \u00e1 112 efnaskiptaferla (KEGG \u2013 Kyoto Encyclopedia of Genes and Genomes). Lykilpr\u00f3tein heilkj\u00f6rnunga voru greind me\u00f0 BUSCO (Benchmarking Universal Single-Copy Orthologs). Erf\u00f0amengi himnusk\u00f3far (Pmemv1.1) inniheldur 96,9% af BUSCO genunum. \u00de\u00e1 leiddi leit me\u00f0 pr\u00f3teinum \u00far skyldum l\u00edfverum \u00ed lj\u00f3s lykilgen \u00ed n\u00e6ringarn\u00e1mi, saml\u00edfi, DNA met\u00fdleringu, RNA mi\u00f0la\u00f0ri \u00fe\u00f6ggun, glyoxalat ferlinu, melan\u00edn myndun og \u00ed ferlum kyn\u00e6xlunar. \u00dat fr\u00e1 \u00feessu var lagt fram l\u00edkan fyrir fl\u00e6\u00f0i n\u00e6ringarefna (kolefni og nitur) \u00ed himnusk\u00f3f. Einnig benda fengnar uppl\u00fdsingar til \u00feess a\u00f0 himnusk\u00f3f s\u00e9 einsleit (homothallic) og geti einnig fj\u00f6lga\u00f0 s\u00e9r me\u00f0 hli\u00f0\u00e6xlun (parasexual). Tv\u00f6 gen, lec-1 og lec-2, sem t\u00e1kna pr\u00f3tein sem l\u00edkjast galekt\u00ednum voru sko\u00f0u\u00f0 og s\u00fdnt a\u00f0 \u00feau hafa breytilega tj\u00e1ningu. Bl\u00e1bakter\u00edur \u00ed \u00feali vir\u00f0ast hafa \u00e1hrif \u00e1 tj\u00e1ningu lec-1, en afur\u00f0ir lec-2 hafa mj\u00f6g breytilega am\u00edn\u00f3s\u00fdrur\u00f6\u00f0, sem bendir til sterkra valkrafta, sem samsvara \u00fe\u00f3 ekki mismunandi ger\u00f0 bl\u00e1bakter\u00eda \u00ed samb\u00fdlinu. Mikil c\u00fdt\u00f3s\u00edn met\u00fdlering (~13.4%) er \u00ed erf\u00f0amenginu, en met\u00fdlering \u00ed \u00fatr\u00f6\u00f0um og innr\u00f6\u00f0um gena er um 2,7% og 8,2%. \u00cd erf\u00f0amengi\u00f0 vantar geni\u00f0 rid, sem er lykilgen fyrir varnir gegn st\u00f6kklum og endurteknum r\u00f6\u00f0um, og engin merki fundust um basabreytingar af \u00feess v\u00f6ldum. \u00deetta er fyrsta v\u00ed\u00f0t\u00e6ka ranns\u00f3knin \u00e1 st\u00f3rsameindum \u00ed fl\u00e9ttum me\u00f0 bl\u00e1bakter\u00edum (cyanolichen) og leggur grunn a\u00f0 frekari sameindaranns\u00f3knum \u00e1 \u00feessu svi\u00f0i. \u00cd vi\u00f0b\u00f3t vi\u00f0 ofangreindar ranns\u00f3knir fannst fl\u00e9tta sem vi\u00f0 n\u00e1nari sko\u00f0un reyndist vera n\u00fd tegund og var h\u00fan nefnd foldarsk\u00f3f (Peltigera islandica).<\/p>\n

Um doktorsefni\u00f0<\/strong><\/p>\n

Sheeba var f\u00e6dd \u00ed Tamilnadu, Indlandi, d\u00f3ttir G. Manoharan, sem starfa\u00f0i fyrir Indlandsher, og M.L. Samathanam, h\u00fasm\u00f3\u00f0ur. H\u00fan \u00e1 yngri br\u00f3\u00f0ur, Marshall, sem er r\u00e1\u00f0gjafi \u00ed uppl\u00fdsingat\u00e6kni.<\/p>\n

Sheeba lauk n\u00e1mi fr\u00e1 St. Joseph’s Cluny Hr. Sec. framhaldssk\u00f3lanum og \u00fatskrifa\u00f0ist me\u00f0 l\u00e1\u00f0i me\u00f0 meistaragr\u00e1\u00f0ur (M.Sc. Og M. Phil.) fr\u00e1 Bharathidasan h\u00e1sk\u00f3la, Indlandi. \u00c1\u00f0ur en h\u00fan h\u00f3f n\u00e1m vi\u00f0 H\u00e1sk\u00f3la \u00cdslands vann h\u00fan nokkur \u00e1r sem fyrirlesari \u00ed Bangalore. H\u00fan t\u00f3k til starfa vi\u00f0 ranns\u00f3knah\u00f3p \u00d3lafs S. Andr\u00e9ssonar \u00e1ri\u00f0 2008 og hlaut styrk til framhaldsn\u00e1ms fr\u00e1 Ranns\u00f3knasj\u00f3\u00f0i H.\u00cd. \u00e1ri\u00f0 2010 til a\u00f0 vinna a\u00f0 ranns\u00f3knum \u00e1 umritunarmengjum og met\u00fdlun erf\u00f0aefnis \u00ed himnusk\u00f3f (Peltigera membranacea).<\/p>\n

Sheeba er gift Dr. Basil Britto Xavier, n\u00fddoktor vi\u00f0 H\u00e1sk\u00f3lann \u00ed Antwerpen, og eiga \u00feau d\u00f3tturina Benita Samara Basil.
<\/strong><\/p>\n

Vi\u00f0bur\u00f0ur \u00e1 Facebook<\/a><\/strong><\/p>\n<\/div><\/div>","protected":false},"featured_media":2054,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_phd_date_start":"2018-12-06T10:00:00+00:00","_phd_date_end":"2018-12-06T12:00:00+00:00","_phd_location":"Askja Stofa 132","_phd_admission":"Allir velkomnir","_phd_thesis_title":"Sameindagreining \u00e1 himnusk\u00f3f (Peltigera membranacea) me\u00f0 kjarns\u00fdrura\u00f0greiningu og l\u00fdsing \u00e1 n\u00fdrri fl\u00e9ttutegund, foldarsk\u00f3f (Peltigera islandica)","_phd_source_url":"https:\/\/gamli.hi.is\/vidburdir\/doktorsvorn_i_liffraedi_sheeba_santhini_basil","_phd_source_node_id":"312151","_phd_source_type":"vidburdir","_phd_member_id":627,"footnotes":""},"phd_school":[96,93],"phd_discipline":[97],"class_list":["post-6143","phd_defence","type-phd_defence","status-publish","has-post-thumbnail","hentry","phd_school-lif-og-umhverfisvisindadeild","phd_school-verkfraedi-og-natturuvisindasvid","phd_discipline-phd-i-liffraedi"],"_links":{"self":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_defence\/6143","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_defence"}],"about":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/types\/phd_defence"}],"version-history":[{"count":0,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_defence\/6143\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/media\/2054"}],"wp:attachment":[{"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/media?parent=6143"}],"wp:term":[{"taxonomy":"phd_school","embeddable":true,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_school?post=6143"},{"taxonomy":"phd_discipline","embeddable":true,"href":"https:\/\/phd.hi.is\/en\/wp-json\/wp\/v2\/phd_discipline?post=6143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}