{"id":5998,"date":"2026-10-19T09:48:21","date_gmt":"2026-10-19T09:48:21","guid":{"rendered":"https:\/\/phd.hi.is\/doktorsvorn\/doktorsvorn-i-lif-og-laeknavisindum-sigridur-julia-quirk\/"},"modified":"2026-10-19T09:48:21","modified_gmt":"2026-10-19T09:48:21","slug":"doktorsvorn-i-lif-og-laeknavisindum-sigridur-julia-quirk","status":"publish","type":"phd_defence","link":"https:\/\/phd.hi.is\/en\/doktorsvorn\/doktorsvorn-i-lif-og-laeknavisindum-sigridur-julia-quirk\/","title":{"rendered":"Doktorsv\u00f6rn \u00ed l\u00edf- og l\u00e6knav\u00edsindum &#8211; Sigr\u00ed\u00f0ur J\u00fal\u00eda Quirk"},"content":{"rendered":"<div class=\"field-items\">\n<div class=\"field-item even\" property=\"content:encoded\">\n<p>\u00deri\u00f0judaginn 30. apr\u00edl n\u00e6stkomandi ver Sigr\u00ed\u00f0ur J\u00fal\u00eda Quirk doktorsritger\u00f0 s\u00edna \u00ed l\u00edf- og l\u00e6knav\u00edsindum vi\u00f0 L\u00e6knadeild H\u00e1sk\u00f3la \u00cdslands. Ritger\u00f0in ber heiti\u00f0: <strong>Serotype and molecular epidemiology of pneumococci in Iceland before and after pneumococcal vaccination. Hj\u00fapger\u00f0a- og sameindafr\u00e6\u00f0ileg faraldsfr\u00e6\u00f0i pneum\u00f3kokka \u00e1 \u00cdslandi fyrir og eftir pneum\u00f3kokka b\u00f3lusetningu.<\/strong><\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p>Andm\u00e6lendur eru dr. William Hanage, d\u00f3sent vi\u00f0 Harvard School of Public Health, og\u00a0Mark van der Linden, forst\u00f6\u00f0uma\u00f0ur German Nationale Reference Center for Streptococci, Aachen \u00ed \u00de\u00fdskalandi.<\/p>\n<p>\u00a0<\/p>\n<p>Umsj\u00f3narkennari var dr. Karl G. Kristinsson, pr\u00f3fessor vi\u00f0 L\u00e6knadeild, og lei\u00f0beinandi dr. Gunnsteinn Haraldsson, fr\u00e6\u00f0ima\u00f0ur. \u00a0Auk \u00feeirra s\u00e1tu \u00ed doktorsnefnd dr. \u00c1sgeir Haraldsson, pr\u00f3fessor vi\u00f0 L\u00e6knadeild, dr. Martha \u00c1. Hj\u00e1lmarsd\u00f3ttir, d\u00f3sent vi\u00f0 s\u00f6mu deild, og dr. Angela B. Breggermann, pr\u00f3fessor vi\u00f0 University of Oxford.<\/p>\n<p>\u00a0<\/p>\n<p>Engilbert Sigur\u00f0sson, pr\u00f3fessor og deildarforseti L\u00e6knadeildar, stj\u00f3rnar ath\u00f6fninni.<\/p>\n<p>\u00a0<\/p>\n<p><strong>\u00c1grip af ranns\u00f3kn<\/strong><\/p>\n<p>Pneum\u00f3kokkar eru mikilv\u00e6gir s\u00fdkingarvaldar \u00ed m\u00f6nnum um allan heim. \u00cd apr\u00edl 2011 var t\u00edu-gilda pneum\u00f3kokka pr\u00f3teintengda b\u00f3luefni\u00f0 (PHiD-CV) innleitt \u00ed ungbarnab\u00f3lusetningar \u00e1 \u00cdslandi. B\u00f3luefninu er \u00e6tla\u00f0 a\u00f0 veita v\u00f6rn \u00feeim hj\u00fapger\u00f0um sem eru l\u00edklegastar til a\u00f0 valda alvarlegum s\u00fdkingum. \u00cd \u00feessari ritger\u00f0 eru \u00e1hrif b\u00f3luefnisins metin me\u00f0 \u00fev\u00ed a\u00f0 sko\u00f0a dreifingu hj\u00fapger\u00f0a, arfger\u00f0a og s\u00fdklalyfjan\u00e6mi pneum\u00f3kokka sem r\u00e6ktast fr\u00e1 heilbrig\u00f0um b\u00f6rnum \u00e1 leiksk\u00f3laaldri, b\u00f6rnum me\u00f0 mi\u00f0eyrnab\u00f3lgu og fullor\u00f0num einstaklingum me\u00f0 lungnab\u00f3lgu fyrir (2009-2011) og eftir (2012-2017) innlei\u00f0ingu b\u00f3luefnisins.<\/p>\n<p>Algengi \u00feess a\u00f0 leiksk\u00f3lab\u00f6rn bera pneum\u00f3kokka \u00ed nefkoki breyttist ekki vi\u00f0 b\u00f3lusetninguna. Stofnar af hj\u00fapger\u00f0um sem b\u00f3luefni\u00f0 veitir v\u00f6rn gegn f\u00e6kka\u00f0i markt\u00e6kt \u00ed \u00f6llum s\u00fdnaflokkum me\u00f0 samhli\u00f0a fj\u00f6lgun \u00e1 stofnum af hj\u00fapger\u00f0um sem b\u00f3luefni\u00f0 veitir ekki v\u00f6rn gegn. Mi\u00f0eyrnas\u00fdnum f\u00e6kka\u00f0i og j\u00e1kv\u00e6\u00f0ar pneum\u00f3kokkar\u00e6ktanir \u00ed s\u00fdnum fr\u00e1 mi\u00f0eyrum og ne\u00f0ri \u00f6ndunarvegum einnig. Stofnum me\u00f0 minnka\u00f0 n\u00e6mi fyrir penisil\u00edni f\u00e6kka\u00f0i eftir b\u00f3lusetningu \u00ed mi\u00f0eyrnas\u00fdnum vegna f\u00e6kkunar stofna af hj\u00fapger\u00f0 19F sem var megin ors\u00f6k \u00f3n\u00e6mis. Hjar\u00f0\u00f3n\u00e6mi hj\u00e1 eldri \u00f3b\u00f3lusettum einstaklingum var s\u00fdnilegt innan fj\u00f6gurra \u00e1ra fr\u00e1 innlei\u00f0ingu b\u00f3luefnisins.<\/p>\n<p>\u00c1rangur af b\u00f3lusetningunni me\u00f0 PHiD-CV var mj\u00f6g g\u00f3\u00f0ur. \u00c1framhaldandi eftirlit me\u00f0 dreifingu hj\u00fapger\u00f0a er \u00fe\u00f3 afar mikilv\u00e6gt vegna val\u00fer\u00fdstings fr\u00e1 b\u00f3luefnunum og fj\u00f6lbreytileika bakter\u00edunnar \u00fear sem a\u00f0rar hj\u00fapger\u00f0ir geta n\u00e1\u00f0 s\u00e9r \u00e1 strik. Afar mikilv\u00e6gt er a\u00f0 tryggja a\u00f0 \u00feau b\u00f3luefni sem standa til bo\u00f0a veiti v\u00f6rn gegn \u00feeim hj\u00fapger\u00f0um sem eru \u00ed umfer\u00f0 hverju sinni.<\/p>\n<p><strong><\/strong><\/p>\n<p><strong>Um doktorsefni\u00f0<\/strong><\/p>\n<p>Sigr\u00ed\u00f0ur J\u00fal\u00eda Quirk er f\u00e6dd \u00e1 Englandi \u00e1ri\u00f0 1976. Foreldrar hennar eru Sigr\u00ed\u00f0ur Ketilsd\u00f3ttir og John B. Quirk. B\u00f6rn hennar eru J\u00fal\u00eda N\u00f3tt, Ind\u00edana L\u00edf og Atli J\u00f6kull. H\u00fan lauk BSc-gr\u00e1\u00f0u \u00ed l\u00edfeindafr\u00e6\u00f0i fr\u00e1 H\u00e1sk\u00f3la \u00cdslands \u00e1ri\u00f0 2010 og vi\u00f0b\u00f3tardipl\u00f3mu til starfsr\u00e9ttinda \u00ed s\u00f6mu grein \u00e1ri s\u00ed\u00f0ar fr\u00e1 sama sk\u00f3la. H\u00fan h\u00f3f meistaran\u00e1m vi\u00f0 L\u00e6knadeild H\u00e1sk\u00f3la \u00cdslands, sem var st\u00e6kka\u00f0 \u00ed doktorsverkefni og unni\u00f0 \u00ed samvinnu vi\u00f0 h\u00e1sk\u00f3lana \u00ed Oxford og Cambridge \u00e1 Englandi.<\/p>\n<\/div><\/div>","protected":false},"featured_media":1210,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_phd_date_start":"2019-04-30T10:00:00+00:00","_phd_date_end":"2019-04-30T12:30:00+00:00","_phd_location":"A\u00f0albygging H\u00e1t\u00ed\u00f0asalur","_phd_admission":"A\u00f0gangur \u00f3keypis","_phd_thesis_title":"Serotype and molecular epidemiology of pneumococci in Iceland before and after pneumococcal vaccination. 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