{"id":5976,"date":"2026-10-19T09:48:17","date_gmt":"2026-10-19T09:48:17","guid":{"rendered":"https:\/\/phd.hi.is\/doktorsvorn\/doktorsvorn-i-lif-og-laeknavisindum-gudrun-dora-bjarnadottir\/"},"modified":"2026-10-19T09:48:17","modified_gmt":"2026-10-19T09:48:17","slug":"doktorsvorn-i-lif-og-laeknavisindum-gudrun-dora-bjarnadottir","status":"publish","type":"phd_defence","link":"https:\/\/phd.hi.is\/en\/doktorsvorn\/doktorsvorn-i-lif-og-laeknavisindum-gudrun-dora-bjarnadottir\/","title":{"rendered":"Doktorsv\u00f6rn \u00ed l\u00edf- og l\u00e6knav\u00edsindum – Gu\u00f0r\u00fan D\u00f3ra Bjarnad\u00f3ttir"},"content":{"rendered":"
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F\u00f6studaginn 19. okt\u00f3ber ver Gu\u00f0r\u00fan D\u00f3ra Bjarnad\u00f3ttir doktorsritger\u00f0 s\u00edna \u00ed l\u00edf- og l\u00e6kna-v\u00edsindum vi\u00f0 L\u00e6knadeild H\u00e1sk\u00f3la \u00cdslands. Ritger\u00f0in ber heiti\u00f0: Notkun meth\u00fdlfen\u00eddats \u00ed \u00e6\u00f0 \u00e1 \u00cdslandi – Algengi notkunar bori\u00f0 saman vi\u00f0 \u00f6nnur \u00f6rvandi efni. Intravenous use of methylphenidate in Iceland-Prevalence and comparison to other psychostimulants. <\/strong><\/p>\n

Andm\u00e6lendur eru dr. Kim Wolff, pr\u00f3fessor vi\u00f0 King\u2018s College \u00ed London, og dr. Kristinn T\u00f3masson, yfirl\u00e6knir Vinnueftirlits r\u00edkisins.<\/p>\n

Umsj\u00f3narkennari og lei\u00f0beinandi var dr. Magn\u00fas Haraldsson, d\u00f3sent vi\u00f0 L\u00e6knadeild, og me\u00f0-lei\u00f0beinandi var dr. Andr\u00e9s Magn\u00fasson ge\u00f0l\u00e6knir. Auk \u00feeirra s\u00e1tu \u00ed doktorsnefnd Bjarni \u00d6ssurarson Rafnar a\u00f0junkt, Engilbert Sigur\u00f0sson pr\u00f3fessor og Magn\u00fas J\u00f3hannsson, pr\u00f3fessor emeritus.<\/p>\n

Dr. Ingibj\u00f6rg Har\u00f0ard\u00f3ttir, pr\u00f3fessor og varadeildarforseti vi\u00f0 L\u00e6knadeild H\u00e1sk\u00f3la \u00cdslands, stj\u00f3rnar ath\u00f6fninni sem fer fram \u00ed H\u00e1t\u00ed\u00f0asal H\u00e1sk\u00f3la \u00cdslands og hefst kl. 9:00.<\/a><\/p>\n

\u00c1grip<\/strong> af ranns\u00f3kn<\/strong><\/p>\n

Bakgrunnur:<\/strong> Met\u00fdlfen\u00eddat (MPH) er \u00f6rvandi lyf og er misnotkun \u00feess vel \u00feekkt. MPH er tali\u00f0 minna \u00e1vanabindandi en \u00f6nnur \u00f6rvandi efni eins og amfetam\u00edn og k\u00f3ka\u00edn en l\u00edti\u00f0 er vita\u00f0 um t\u00ed\u00f0ni og einkenni misnotkunar \u00feess \u00ed \u00e6\u00f0.<\/p>\n

Markmi\u00f0:<\/strong> A\u00f0 sko\u00f0a t\u00ed\u00f0ni og einkenni misnotkunar MPH \u00ed \u00e6\u00f0 mi\u00f0a\u00f0 vi\u00f0 \u00f6nnur \u00f6rvandi efni og a\u00f0 rannsaka hvort \u00e1kve\u00f0in lyfjaform MPH s\u00e9u notu\u00f0 fremur en \u00f6nnur. Einnig a\u00f0 sko\u00f0a hvernig sprautunotendur leysa efnin upp og a\u00f0 m\u00e6la magn MPH \u00feegar \u00feau eru tilb\u00fain til notkunar.<\/p>\n

A\u00f0fer\u00f0:<\/strong> \u00d6llum sem voru a\u00f0 hefja f\u00edknime\u00f0fer\u00f0 og h\u00f6f\u00f0u nota\u00f0 v\u00edmuefni \u00ed \u00e6\u00f0 undanfarna 30 daga var bo\u00f0in \u00fe\u00e1tttaka. Notast var vi\u00f0 h\u00e1lfsta\u00f0la\u00f0an spurningarlista og voru \u00fe\u00e1tttakendur 108. Einnig voru h\u00f3pur notenda MPH \u00ed \u00e6\u00f0 og h\u00f3pur heilbrig\u00f0ra fengnir til a\u00f0 leysa fj\u00f3rar ger\u00f0ir af MPH lyfja upp og gera \u00feau tilb\u00fain til notkunar \u00ed \u00e6\u00f0. Magn MPH var m\u00e6lt \u00ed upplausnunum.<\/p>\n

Ni\u00f0urst\u00f6\u00f0ur:<\/strong> Misnotkun MPH \u00ed \u00e6\u00f0 er algeng \u00e1 \u00cdslandi og h\u00f6f\u00f0u 88% \u00fe\u00e1tttakenda nota\u00f0 \u00fea\u00f0 \u00ed \u00e6\u00f0 undanfarinn m\u00e1nu\u00f0. Sprautunotendur v\u00f6ldu MPH fremur en \u00f6nnur v\u00edmuefni og meirihluti valdi a\u00f0 nota eitt af langvirkum formum lyfsins, MPH SR. B\u00e1\u00f0ir h\u00f3par n\u00e1\u00f0u a\u00f0 leysa upp yfir 50% af stuttverkandi (MPH IR) og langvirku MPH en minna en 20% \u00far osmot\u00edsku formunum MPH OROS og MPH OCR.<\/p>\n

\u00c1lyktanir:<\/strong> Notkun MPH \u00ed \u00e6\u00f0 er algeng \u00e1 \u00cdslandi og flestir kj\u00f3sa a\u00f0 nota \u00fea\u00f0 fremur en \u00f6nnur efni. Ni\u00f0urst\u00f6\u00f0urnar benda til \u00feess a\u00f0 vel s\u00e9 h\u00e6gt a\u00f0 misnota MPH en misnotkunarh\u00e6tta er mismikil eftir MPH lyfjaformum.<\/p>\n

Abstract<\/strong><\/p>\n

Background<\/strong>: Methylphenidate (MPH) is a psychostimulant which has known abuse potential. Subjective effects and consumption patterns of i.v. MPH use has not been investigated.<\/p>\n

Aims<\/strong>: To investigate the prevalence and subjective effects of i.v. MPH misuse and to compare it to misuse of other psychostimulants. To investigate how much MPH people who inject drugs (PWID) can disintegrate from different MPH preparations.<\/p>\n

MM<\/strong>: All those who had used i.v. substances 30 days before entering addiction treatment were offered to participate. A semi-structured questionnaire was used and a total of 108 participated. Groups of i.v. MPH users and healthy subjects disintegrated MPH from four MPH formulations and the amount of MPH was measured.<\/p>\n

Results<\/strong>: A majority of participants (88%) had used i.v. MPH during the previous 30 days. MPH was both the most commonly used and preferred i.v. substance. A majority used and preferred sustained release MPH. Both PWID and non-users disintegrated over 50% from MPH IR and MPH SR but significantly less from the osmotic formulations (<20%).<\/p>\n

Conclusions<\/strong>: I.v. MPH misuse is very common among PWID and it is currently the most commonly used and preferred i.v. substance in Iceland. One of the long-acting MPH formulations (MPH SR) was preferred by PWID.<\/p>\n

Um doktorsefni\u00f0<\/strong><\/p>\n

Gu\u00f0r\u00fan D\u00f3ra Bjarnad\u00f3ttir er f\u00e6dd \u00e1ri\u00f0 1982 \u00ed Reykjav\u00edk. H\u00fan lauk st\u00fadentspr\u00f3fi af st\u00e6r\u00f0fr\u00e6\u00f0ibraut Verzlunarsk\u00f3la \u00cdslands \u00e1ri\u00f0 2002 og emb\u00e6ttispr\u00f3fi \u00ed l\u00e6knisfr\u00e6\u00f0i fr\u00e1 University of Debrecen \u00ed Ungverjalandi \u00e1ri\u00f0 2009. H\u00fan lauk s\u00e9rn\u00e1mi \u00ed ge\u00f0l\u00e6kningum \u00e1ri\u00f0 2015 og hefur starfa\u00f0 s\u00ed\u00f0an sem ge\u00f0l\u00e6knir \u00e1 ge\u00f0deild Landsp\u00edtalans. Gu\u00f0r\u00fan D\u00f3ra er d\u00f3ttir Au\u00f0ar Gu\u00f0j\u00f3nsd\u00f3ttur skur\u00f0stofuhj\u00fakrunarfr\u00e6\u00f0ings og Bjarna Halld\u00f3rssonar skipstj\u00f3ra. Eiginkona Gu\u00f0r\u00fanar D\u00f3ru er \u00c1sta R\u00fan Valger\u00f0ard\u00f3ttir s\u00e1lfr\u00e6\u00f0ingur og eiga \u00fe\u00e6r drengina Bjarna Frey 4 \u00e1ra og Gylfa Bj\u00f6rn 7 m\u00e1na\u00f0a.<\/p>\n<\/div><\/div>","protected":false},"featured_media":1154,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_phd_date_start":"2018-10-19T09:00:00+00:00","_phd_date_end":"2018-10-19T12:00:00+00:00","_phd_location":"A\u00f0albygging H\u00e1t\u00ed\u00f0arsalur","_phd_admission":"A\u00f0gangur \u00f3keypis","_phd_thesis_title":"Notkun meth\u00fdlfen\u00eddats \u00ed \u00e6\u00f0 \u00e1 \u00cdslandi - Algengi notkunar bori\u00f0 saman vi\u00f0 \u00f6nnur \u00f6rvandi efni. 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